Episode 11: Detox
Aired 2/15/05
A teenage couple decides to go for a drive in his dads Porsche.
The boy, named Keith, begins choking and coughing up blood. Distracted,
the girl spins the car out and they are broadsided by a bus.
Cameron presents the case: the 16-year old victim of M.V.A. has
been in an out of the hospital with internal bleeding for three
weeks. House attributes it to the car crash, but Cameron says the
bleeding started before the crash. House is more interested in getting
his Vicodin prescription refilled but the pharmacy is empty. Cuddy
sees House popping more Vicodin and challenges him to quit his addiction.
He says he takes it to treat the pain, so she offers a month free
from clinic duty if he goes a week without pills.
Cameron mentions that the victim has non-inherited hemolytic anemia,
which is incredibly rare. House dismisses it as meningitis, but
thats not it either. He calls his group together and tells
them they have to figure out why the patients red blood cells
are supplying oxygen to the body. House instructs them to run tests
for an infection, as well as Lupus, drug use and cancer.
In talking to the patients father, Cameron learns that Keiths
girlfriend was formerly in rehab and that his mother died of pancreatic
cancer. The radioimmunoassay test is negative on drug use. A Gallium
scan shows no infection and a radioactive isotope injected into
the bloodstream shows no inflammation. The Lupus test comes up negative
as well. Wilson performs a biopsy to check for lymphoma, but that
too is wrong.
While the doctors mull other possibilities, Keith complains that
he has something in his eye. The doctors find nothing, but Keith
still cant see. Foreman observes a retinal clot. However,
any treatment for the clot would kill him because of his low blood
flow. They have two hours to save either his eye or his life. House
asks his team how something could be causing both internal bleeding
and clotting. Infection causes clotting, so what would be hiding
from the Gallium scan? It must be a cardiac clot that flicks off
and travels to the eye.
Chase performs an echocardiogram on Keiths heart, but begrudgingly
admits that they are not going to treat his eye. The blindness will
become permanent. Chase later tells House that the test showed no
cardiac infection. House has him up the antibiotics. Chase thinks
he can remove some liquid from the eye itself to make room for the
clot to move out on its own. Chase leaves and House backs against
a wall. Hes in tremendous pain.
With a needle, Chase removes some vitreous humor from the eye which
helps Keith see again. After the procedure, Keiths girlfriend
comes in and kisses him. He vomits. The doctors rush him to the
ICU. His liver is shutting down and he is dying. Keiths father
is enraged. Cameron asks House if proving Cuddy wrong is worth all
of this.
The team wonders what would cause liver damage. Hemolytic anemia
is ruled out. House suggests hepatitis-E, even though Lupus is more
likely. House thinks they need to rule out hep-E because it has
no treatment, so he instructs the group to give Keith mendrol, which
will react with the hep-E to make him worse. If not, theyll
know that Lupus is the cause. Outside, Foreman tells Cameron that
House is detoxing from Vicodin and is losing his mind. In his office,
House sweats in pain.
Cameron tells Keiths father that she believes his son is
afflicted with Lupus. To distract himself from the pain, House smashes
himself with a paperweight and breaks a bone in his hand. As Cameron
is treating him, Cuddy demands to know why House had Cameron lie.
Now Keiths father wants his son either treated for Lupus or
transferred. But when Cameron tells him that Keith is too weak to
be moved, he relents.
Chase and Cameron prepare to begin the treatment and Keith starts
to hallucinate. Cameron notices that Keith is bleeding profusely
from the rectum and is going into hypovolemic shock. An angiography
later reveals major internal bleeding, severe hemodynamic compromise
and complete liver failure. Cameron says that hallucinations are
from psychosis, which proves that Lupus is the cause. Shes
angry that they had to dally with hep-E because Keith needs a new
liver. House still thinks Lupus is the wrong diagnosis, but he asks
for Keith to be moved to the top of transplant list anyway.
In his office, House vomits from the pain. Foreman comes in with
a bottle of Vicodin so that he can recover to treat Keith. Cameron
and Chase break it to Keiths father that the Lupus is too
advanced to treat and the transplant list has over 15,000 patients.
House is still pondering who the Jules is that Keith
yelled out during his hallucination. Keiths father informs
them that Jules is their cat who died about a month ago. The girlfriend
says that Jules slept in the bed with Keith.
Foreman and Chase exhume the cat. House does an autopsy. At the
same time, an emergency liver comes in. Keith is taken into the
OR and is prepped. Houses rushes in to stop the surgery, announcing
that Keith doesnt have lupoid Hepatitis. He has acute naphthalene
toxicity from termites. Termites create the toxin to protect their
nests, and judging from the contents of Jules stomach, Keiths
bedroom was also infested with termites. The surgeon refuses to
stop, so House spits on him to spread germs everywhere.
In the hallway, the group refuses to believe Houses new diagnosis.
If it was environmental, Keith would have improved in the hospital.
But House explains that naphthalene is fat soluble. Keith was repulsed
by the hospital food and hadnt eaten much, so his body started
burning fat and the poison poured into his system. Keiths
father punches House in the face. House promises that 24 hours of
calorie intake will heal Keith. If they do the surgery, it wont
solve anything.
Foreman and Chase hammer open a wall in Keiths home bedroom.
Termites pour out. House was right. Back at the hospital, Keith
is rapidly improving. And House made it through the week without
any pills. He comes to the realization that hes addicted,
but since he is functioning hell just keep taking the drugs.
Wilson yells at him for changing in the last few years and becoming
miserable. Hes using his leg and the drugs as an excuse.
- From Fox.com
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